Description
Rejuran I (Eye) is an elite, sterile injectable treatment engineered specifically to treat the highly delicate, thin, and sensitive periorbital (eye contour) zone. Developed by PharmaResearch Product (South Korea), this advanced clinical formulation is powered by highly purified Polynucleotides (PN) extracted from salmon DNA utilizing proprietary DOT™ (DNA Optimizing Technology). Recognizing that heavy, dense gels can cause chronic fluid retention and unnatural lumps around the eyes, Rejuran I is meticulously structured as a low-viscosity, high-fluidity formulation. It spreads effortlessly through the fragile periocular skin layers, working at a cellular level to erase crow’s feet, clear dark circles, and rebuild a thinned dermal matrix.
Main Benefits of Rejuran I
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Ultra-Low Viscosity Safety: Low-density fluidity ensures a smooth, uniform micro-diffusion across the fragile skin of the eyelids, eliminating the risk of surface lumps or chronic under-eye puffiness.
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Endogenous Skin Re-Thickening: Actively triggers fibroblasts to synthesize fresh Type I collagen and elastin networks, reinforcing and thickening paper-thin periocular skin.
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Vascular Dark Circle Reduction: Strengthens the capillary structures and improves local dermal density under the eyes, reducing the transparency that reveals dark, hollow vascular shadows.
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Fine Line & Crow’s Feet Smoothing: Naturally smooths out fine dynamic lines, dehydration lines, and structural laughter creases bordering the eyes.
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Accelerated Tissue Repair: Speeds up metabolic recovery and cellular division within fatigued or sun-damaged eye contours, restoring a youthful, wide-awake brightness.
Indications
Rejuran I is precisely indicated for superficial to mid-dermal micro-injection to remodel and heal the periorbital tissue matrix:
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Periorbital Fine Lines (Crow’s Feet): Smoothing out static and dynamic surface wrinkles surrounding the outer corners of the eyes.
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Thinned, Crepey Under-Eye Skin: Re-densifying fragile, loose skin structures on the lower and upper eyelids.
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Vascular Dark Circles: Brightening dark shadows caused by poor blood flow and thinning dermal layers.
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Tear Trough Dehydration Lines: Re-hydrating and plumping up fine, hollow structural lines beneath the eyes.
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Post-Procedural Eye Recovery: Serving as an ideal companion treatment alongside fractional lasers, eye microneedling, or plasma pen therapies to optimize regenerative outputs.
Technical Specifications
| Feature | Specification |
| Product Name | Rejuran I (Eye) |
| Manufacturer | PharmaResearch Product (South Korea) |
| Active Ingredient | Highly Purified Polynucleotide (PN – Salmon DNA Derived) |
| Viscosity & Density | Ultra-Low (Calibrated specifically for fragile eye tissues) |
| Category | Regenerative Eye Bioremodeler / Periocular Mesotherapy |
| Packaging | 1 x 1ml Pre-filled syringe per box |
| Needles Included | 2 x 34G ultra-fine sterile needles |
| Application Layer | Superficial to mid-dermis (Periocular) |
| Treatment Interval | 3 sessions spaced 4 weeks apart |
| Storage | Store between 2°C to 25°C; protect from freezing and direct light |
Mechanism of Action
The formulation operates through Cellular Base Rescue & Microvascular Regeneration:
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Immediate Interstitial Spreading: Upon precise injection, the high-fluidity PN gel diffuses smoothly into the thin dermal layers under the eyes without gathering into tense fluid pockets or drawing excess water.
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Purinergic Receptor Signaling: The highly purified PN chains anchor to cellular purinergic ($A2A$) receptors, shutting down local inflammatory cascades and shifting tired skin cells into a high-rate healing cycle.
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DNA Salvage Pathway Activation: By supplying pre-cleaved purine and pyrimidine bases directly to the tissue, it allows local cells to fast-track DNA replication and cellular division without heavy energy consumption.
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Capillary Wall Optimization: Stimulates localized microvascular repair (angiogenesis), enhancing nutrient and oxygen supply to brighten skin and clear fluid accumulations under the eyes.
Administration Protocol
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Technique: Administered exclusively by a licensed professional utilizing the micro-papule technique, detailed nappage, or retrograde linear threading across superficial eye lines.
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Injection Tool: Delivered utilizing the provided ultra-fine 34G needles (among the thinnest needles in aesthetic medicine) to maximize patient comfort and drastically reduce bruising risks.
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Injection Depth: Must be placed strictly into the superficial to mid-dermis. Injecting too deeply into the subcutaneous fat compartments misses the thinning dermal skin layer, while overly superficial placement under the absolute outer epidermis can extend papule absorption time.
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Treatment Regimen: A full corrective cycle requires an initial series of 3 sessions, spaced exactly 4 weeks apart. A maintenance treatment every 6 months is recommended to sustain the youthful, re-densified results.
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Post-Treatment Guidelines: Small micro-papules (tiny bumps), light swelling, and mild localized redness are standard physiological responses that fade naturally within 24 to 48 hours. Patients must skip eye makeup for 24 hours, avoid rubbing the eye zones, and stay away from saunas and heavy workouts for 48 hours.
FAQ
Q: How does Rejuran I differ from Rejuran Healer and Rejuran S?
A: All three rely on pure Polynucleotides (PN), but their gel viscosity is optimized for separate skin structures. Rejuran Healer is a medium-viscosity gel designed for broad-scale facial hydration and elasticity. Rejuran S is an ultra-dense, thick gel engineered to stay localized beneath depressed acne scars. Rejuran I is the thinnest, most liquid formulation in the family, crafted specifically to flow smoothly through the delicate, thin skin around the eyes without causing lumps.
Q: Is Rejuran I an under-eye filler?
A: No. Traditional dermal fillers use cross-linked Hyaluronic Acid to create instant mechanical volume and fill deep tear trough hollows. Rejuran I is a regenerative skin healer; it does not add artificial volume or draw heavy water weight. Instead, it thickens your skin from within by growing fresh, natural collagen layers, making it completely safe for individuals prone to morning eye bags.
Q: Can Rejuran I be combined with botulinum toxins or fillers?
A: Yes, absolutely. While Botox relaxes dynamic muscles to stop crow’s feet and fillers restore deep bone volume deficits, Rejuran I repairs the actual quality and thickness of the overlying skin. It is highly recommended to wait 10 to 14 days between different injectable protocols.
IMPORTANT NOTICE ON INTELLECTUAL PROPERTY
This store operates as an autonomous merchant of genuine medical aesthetic products. We maintain no formal affiliation, partnership, or authorized distribution agreement with PharmaResearch Product or the Rejuran brand family. All proprietary names, logos, and trademarks mentioned herein remain the exclusive intellectual property of their rightful owners. Their use on this site is strictly for the identification and description of the original goods we provide as an independent reseller.
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