Description
Rejuran TrueSkin Essence (popularly known as Rejuran Healer) is a revolutionary, clinical-grade skin-remoldeling treatment designed to reverse signs of aging and restore skin health at a cellular level. Formulated with high-purity Polynucleotides (PN) extracted from salmon DNA, this advanced skin booster goes beyond superficial hydration. It functions as a biological cell-activator, repairing the skin from the inside out by rebuilding the dermal matrix, increasing skin thickness, and establishing an optimal environment for natural skin regeneration.
Main Benefits of Rejuran TrueSkin Essence
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Dermal Matrix Reconstruction: Increases the thickness and density of the skin’s dermal layer, reinforcing its structural integrity and filling out fine lines.
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Biological Cellular Repair: Salmon-derived PN fragments activate sluggish fibroblasts, triggering a massive boost in natural collagen and elastin synthesis.
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Excellent Hydro-Balancing: Noticeably balances sebum production while optimizing internal hydration levels, reducing both oiliness and dry patches.
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Elasticity & Firmness Restoration: Tightens sagging skin and restores natural elasticity, providing a subtle, organic lifting effect across the entire face.
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Skin Barrier Fortification: Repairs a compromised epidermis, reducing sensitivity, redness, and inflammation caused by environmental damage or harsh cosmetic procedures.
Indications
Rejuran TrueSkin Essence is highly indicated for full-face structural rejuvenation:
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Chronological Aging & Photoaging: Correcting fine lines, wrinkles, and thinned skin texture.
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Enlarged Pores & Rough Microrelief: Refining skin texture and closing pores by tightening the surrounding dermal tissue.
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Acne Aftermath: Softening light atrophic scarring and clearing up post-inflammatory marks.
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Dull & Exhausted Complexions: Restoring a vibrant, healthy “salmon-glow” to skin drained by stress or pollution.
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Pre- and Post-Procedure Prep: Strengthening the skin barrier before or after fractional laser and chemical peel treatments.
Technical Specifications
| Feature | Specification |
| Product Name | Rejuran TrueSkin Essence (Rejuran Healer) |
| Manufacturer | PharmaResearch Products (South Korea) |
| Active Ingredient | Polynucleotide (PN) 2% |
| Viscosity | Medium (Optimized for fluid, full-face intradermal diffusion) |
| Packaging | 2 x 2ml Pre-filled syringes per box |
| Needle Size | Ultra-fine mesotherapy needles included |
| Storage | Store at room temperature (1°C to 30°C) away from light |
Mechanism of Action
The essence operates through Biocompatible DNA Scaffold Induction:
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Scaffold Provision: Upon injection, the long-chain PN molecules form a temporary physical matrix in the dermis, supporting immediate cell anchoring.
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Fibroblast Proliferation: The nucleotides break down gradually, binding to specific cell receptors that instruct fibroblasts to rapidly multiply and synthesize extracellular matrix proteins.
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Angiogenesis Support: It promotes micro-vascularization (the formation of tiny blood vessels), vastly improving skin oxygenation and nutrient delivery.
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Scavenging Free Radicals: The chemical structure of PN acts as a shield, trapping and neutralizing destructive free radicals to prevent further cellular aging.
Administration Protocol
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Technique: Administered via the micro-papule technique (creating tiny dots across the treatment zone), nappage, or via specialized multi-needle mesotherapy injectors.
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Injection Depth: Intradermal layer (superficial to mid-dermis) utilizing an ultra-fine 33G or 34G needle.
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Treatment Cycle: A standard foundational protocol requires 3 to 4 sessions spaced exactly 3 to 4 weeks apart.
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Maintenance: To preserve the deep regenerative cellular changes, a single top-up treatment is recommended every 6 months.
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Professional Note: Small papules will form at the injection sites. This is entirely normal and expected; the viscous PN gel naturally diffuses and absorbs completely into the surrounding tissue within 24 to 48 hours.
FAQ
Q: How does Rejuran TrueSkin Essence differ from traditional Hyaluronic Acid (HA) skin boosters?
A: Traditional HA boosters simply attract water to provide temporary plumpness and hydration. Rejuran PN does not rely on water retention; it actively forces the body to grow its own new skin layers, collagen, and blood vessels, resulting in true, long-lasting structural healing.
Q: Is the treatment painful?
A: Because PN has a slightly higher viscosity than water, a mild stinging sensation can occur during injection. Applying a high-potency topical numbing cream (like Neo-Cain) for 20–30 minutes prior to the procedure ensures excellent patient comfort.
Q: When do the final results become visible?
A: Skin texture and oil-moisture balance typically improve within the first 1–2 weeks. Structural improvements, such as enhanced elasticity, pore reduction, and a visible thickening of the skin barrier, unfold progressively over 4 to 6 weeks as the new cell matrix matures.
IMPORTANT NOTICE ON INTELLECTUAL PROPERTY
This store operates as an autonomous merchant of genuine medical aesthetic products. We maintain no formal affiliation, partnership, or authorized distribution agreement with PharmaResearch Products, its subsidiaries, or the Rejuran brand family. All proprietary names, logos, and trademarks mentioned herein remain the exclusive intellectual property of their rightful owners. Their use on this site is strictly for the identification and description of the original goods we provide as an independent reseller.




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