Neuramis Volume Lidocaine Filler

Description

Neuramis Volume Lidocaine is the most robust, high-viscosity injectable dermal filler within the professional aesthetic line developed by Medytox (South Korea). Specially engineered for deep structural tissue remodeling, non-surgical facial bone sculpting, and the correction of severe dermal folds, it delivers powerful structural support. Manufactured using Medytox’s proprietary SHAPE™ Technology (Stabilized Hyaluronic Acid & Purified Execution), this formulation undergoes an intensive two-step cross-linking process followed by an exhaustive purification cycle. This protocol maximizes cross-linking efficiency while thoroughly removing unlinked BDDE residues and minimizing trace proteins. Neuramis Volume exhibits a high elastic modulus (G-Prime), providing maximum mechanical lifting power, outstanding resistance against deformation, and stable tissue projection. Infused with 0.3% Lidocaine Hydrochloride to eliminate procedural pain, it safely integrates within deep subcutaneous or supra-periosteal tissue planes to restore sharp facial definition and youthfully balanced contours.

Main Benefits of Neuramis Volume Lidocaine

• Maximum Structural Lifting & Projection: Engineered with a dense, highly cohesive cross-linked network that provides the strong mechanical lifting power needed to sculpt bone contours and fill severe tissue depressions.

• SHAPE™ Technology Safety Profile: Advanced multi-stage purification ensures minimal residual chemical cross-linkers, drastically lowering the risk of post-procedure swelling, edema, or late-onset inflammatory reactions.

• Highly Stable Shape Retention: The uniform, high-density gel mass resists migration and holds its structural shape beautifully, making it ideal for sharp, defined facial contouring.

• Integrated Local Anesthetic: Formulated with 0.3% Lidocaine Hydrochloride to effectively numb deep tissue layers, delivering a painless and highly comfortable treatment experience during deep structural delivery.

• Extended Viscoelastic Longevity: The ultra-concentrated, cross-linked HA matrix highly resists natural breakdown by hyaluronidase enzymes, keeping tissue looking beautifully full and stable for 12 to 24 months.

Indications

Neuramis Volume Lidocaine is specifically indicated for deep subcutaneous or supra-periosteal (on bone) injections to reshape facial bone structure, restore deep fat pads, and smooth out severe folds:

• Chin Augmentation & Projection: Correcting weak, recessed chins and lengthening the chin profile for an improved facial balance.

• Jawline Contouring & Definition: Creating a sharp, sculpted mandibular angle and defining a continuous jawline perimeter.

• Cheekbone & Malar Volumization: Rebuilding depleted submalar fat structures and augmenting flat, hollow cheekbones.

• Nose Reshaping (Non-Surgical Rhinoplasty): Straightening nasal dorsal humps, defining the nasal bridge, and projecting the nasal tip.

• Severe Nasolabial Folds: Filling deep, heavy facial expression creases that run from the nose down to the corners of the mouth.

Technical Specifications

Feature	Specification
Product Name	Neuramis Volume Lidocaine
Manufacturer	Medytox Inc. (South Korea)
Active Substrate	Cross-Linked Hyaluronic Acid (HA) of non-animal origin
HA Concentration	20 mg/mL
Local Anesthetic	Lidocaine Hydrochloride (0.3% w/v)
Crosslinking Tech	BDDE cross-linked via SHAPE™ Technology
Packaging Layout	1 x 1.1ml Pre-filled sterile single-use glass syringe per box
Total Fluid Yield	1.1ml total treatment volume per retail box
Included Needles	2 x 27G 1/2″ sterile single-use needles
Injection Layer	Deep subcutaneous layer or supra-periosteal (directly on bone)
Duration of Results	12 to 24 months (depending on individual metabolic rates and area treated)
Storage Parameters	Store between 2°C to 25°C; protect from extreme heat, direct sunlight, and freezing

Mechanism of Action

Neuramis Volume Lidocaine restores high-definition volume through a cohesive Hydrophilic Structural Volumization pathway:

1. Immediate Mechanical Cushioning: Upon deep delivery, the dense monophasic HA gel acts as a solid mechanical cushion. It lifts the overlying skin layers, fills deep tissue voids, and mimics bone structure to create sharp facial definition.

2. Hydrophilic Water Retention: The non-animal HA molecules absorb surrounding water molecules up to 1,000 times their own weight, expanding slightly into tissue gaps to provide long-lasting internal hydration and volume stability.

3. Resilient Cross-Linked Matrix Retention: Thanks to SHAPE™ processing, the tightly bound HA chains resist rapid breakdown by endogenous hyaluronidase enzymes. The gel degrades evenly over months, maintaining a stable lifting effect throughout its lifecycle.

Administration Protocol

• Delivery Formats: Administered exclusively by licensed medical professionals using precise injection techniques. This product is typically delivered via bolus technique directly onto the bone for chin or malar projection, or through linear retrograde threading and fanning patterns using a 25G / 27G blunt micro-cannula to treat deep folds and jaw contours safely.

• Optimal Placement Depth: Must be placed cleanly within the deep subcutaneous fat layer or supra-periosteally. Shallow delivery in the superficial or mid-dermis must be strictly avoided, as the high density of this thick gel can cause hard visible lumps, uneven skin texture, or a bluish tint under the skin (Tyndall effect).

• Post-Injection Management: The injector should firmly mold and massage the treated areas immediately following delivery to blend the gel smoothly into natural facial contours. Patients may notice mild swelling, redness, or localized bruising. Advise them to avoid heavy exercise, alcohol, saunas, and applying heavy pressure to the treated zones for 24 to 48 hours.

FAQ

Q: Can Neuramis Volume Lidocaine be dissolved if needed?

A: Yes. Because Neuramis Volume is composed entirely of cross-linked hyaluronic acid, it can be quickly and completely dissolved using standard prescription hyaluronidase enzymes if a correction or complete reversal is needed.

Q: What makes Neuramis Volume different from Neuramis Deep?

A: The difference lies within the gel’s particle thickness and structural density. Neuramis Deep features a medium-density gel tailored for the mid-to-deep dermis, making it ideal for moderate wrinkles and full lip augmentation. Neuramis Volume is much denser and thicker, designed strictly for deep subcutaneous or bone-level placement to provide heavy structural lifting on the chin, cheeks, nose, and jawline.

Q: Can this product be used for lip fillers or under-eye hollows?

A: No. Neuramis Volume is strictly contraindicated for highly dynamic, thin-skinned facial zones like the body of the lips or the tear troughs. Its high density and thickness are highly prone to causing hard nodules, visible lumps, and asymmetry in those delicate regions.

IMPORTANT NOTICE ON INTELLECTUAL PROPERTY

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