Description
Natural Skin Restoration with KARISMA Rh Collagen
KARISMA is a pioneering ‘softfiller’ that represents the next frontier in bio-restitutive medicine. Unlike traditional fillers, KARISMA is composed of R-polypeptide chain alpha-1, a recombinant human collagen produced from silkworms. This is combined with high molecular weight hyaluronic acid and carboxymethylcellulose. This unique synergy allows KARISMA to act as a powerful biostimulator that naturally restores the skin’s basement membrane and stimulates the production of type I collagen fibers. It is designed for patients who want to improve skin texture, reduce laxity, and achieve a firming effect through natural physiological pathways.
Biocompatibility and the Power of Rh Collagen
The standout feature of KARISMA is its high safety profile and biocompatibility. Because the collagen is recombinant and non-animal based, there is no risk of allergic reactions or cross-species contamination. The hyaluronic acid in the formula provides an immediate hydrating and plumping effect, while the carboxymethylcellulose acts as an anti-aging agent by inhibiting the activity of hyaluronidase enzymes. This ensures that the regenerative effects are both immediate and long-lasting. After injection, the skin undergoes a deep remodeling process that improves density and elasticity without the ‘over-filled’ look of traditional volumizers.
Indications and Treatment Protocol
KARISMA is primarily indicated for the correction of small skin imperfections on the face, neck, and décolletage. it is highly effective for smoothing fine lines, reducing the appearance of small scars (such as acne scars), and defining facial contours. The typical protocol involves two sessions spaced one month apart, with a maintenance session every six months. The gel is injected into the mid-dermis using a 27G or 30G needle. Patients experience minimal downtime, with a visible ‘glow’ and improved skin tightness appearing shortly after the first treatment.
Standards and Safety Compliance
As a CE-certified medical device, KARISMA must be administered exclusively by qualified healthcare professionals. To maintain high standards, it is vital to communicate to patients that this is a regenerative treatment, not a volumetric filler. Practitioners must ensure the product is stored at room temperature and away from direct light. Contraindications include active autoimmune diseases or skin infections. Always source KARISMA through verified wholesale supplies to guarantee the purity and authenticity of the recombinant collagen chains.






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