Description
Rejuran S (Scar) is an elite, sterile injectable bioremodeler engineered specifically to treat deep, depressed scars, severe acne scarring, and deep structural depressions. Developed by PharmaResearch Product (South Korea), this advanced clinical formulation is powered by highly purified Polynucleotides (PN) extracted from salmon DNA utilizing proprietary DOT™ (DNA Optimizing Technology). Boasting a significantly higher viscosity and gel density than classic Rejuran formulations, Rejuran S functions as a stable physical framework that fills structural dermal valleys while aggressively triggering local cellular regeneration and collagen synthesis exactly where the tissue matrix has collapsed.
Main Benefits of Rejuran S
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Targeted Atrophic Scar Correction: Viscous gel matrix provides an immediate, stable structural lift beneath deep acne scars (boxcar, rolling, ice-pick) and post-traumatic scars.
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Aggressive Fibroblast Proliferation: Actively signals native fibroblasts to multiply and rebuild a healthy, organic extracellular matrix.
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Endogenous Collagen Synthesis: Drives the synthesis of brand-new Type I and Type III collagen, gradually re-thickening thinned, scarred skin layers from within.
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Advanced Angiogenesis: Promotes microvascular repair and new blood vessel formation, boosting blood flow and accelerating tissue clearing in chronic scar zones.
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Long-Lasting Cellular Remodeling: High-density PN molecules resist rapid enzymatic clearance, providing an extended therapeutic window for sustained structural healing.
Indications
Rejuran S is precisely indicated for deep dermal micro-injection to remodel structural depressions and fibrous tissue scars:
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Severe Acne Scarring: Flattening stubborn boxcar scars, rolling scars, and matching out uneven skin textures left by cystic acne.
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Atrophic & Post-Traumatic Scars: Correcting sunken scars resulting from surgical incisions, accidents, or chickenpox.
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Deep Stretch Marks (Striae): Repairing localized linear dermal fractures on highly stretched tissue areas.
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Localized Deep Wrinkles: Filling and remodeling solitary, deep-set structural creases that resist lighter skin boosters.
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Post-Laser Skin Recovery: Serving as an ideal sub-cision or fractional laser companion treatment to optimize regenerative skin outputs.
Technical Specifications
| Feature | Specification |
| Product Name | Rejuran S (Scar) |
| Manufacturer | PharmaResearch Product (South Korea) |
| Active Ingredient | Highly Purified Polynucleotide (PN – Salmon DNA Derived) |
| Viscosity & Density | Ultra-High (Engineered for structural scar filling) |
| Category | Skin Bioremodeler / Regenerative Scar Mesotherapy |
| Packaging | 1 x 1ml Pre-filled syringe per box |
| Needles Included | 2 x 30G 1/2″ ultra-fine sterile needles |
| Application Layer | Deep dermis (directly beneath the scar tissue) |
| Treatment Interval | 3 to 4 sessions spaced 4 weeks apart |
| Storage | Store between 2°C to 25°C; protect from freezing and direct light |
Mechanism of Action
The formulation operates through Mechanical Framework Scaffolding & Cellular Repatterning:
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Immediate Structural Cushioning: Upon targeted deep dermal injection, the dense PN gel acts as a physical mesh that pushes up the depressed floor of the scar, instantly improving surface smoothness.
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Scavenger Receptor Activation: The highly purified PN molecules bind to specific cellular purinergic ($A2A$) receptors, triggering an immediate anti-inflammatory signaling pathway and switching skin cells into repair mode.
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DNA Base Rescue Pathway: As the polynucleotides gradually break down into smaller nucleotides, they feed local cells directly, bypassing energy-heavy synthesis routes to accelerate cell division.
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Fibrotic Tissue Uncoupling: When combined with sub-cision, Rejuran S acts as a biological shield that prevents old, fibrous scar bands from re-attaching to the underlying tissue, allowing a flat surface layer to heal permanently.
Administration Protocol
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Technique: Administered exclusively by a licensed professional using the micro-droplet technique or precise retrograde linear threading directly beneath each individual scar valley. It is frequently combined with manual sub-cision (breaking the underlying scar fibers).
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Injection Tool: Delivered utilizing the provided 30G needles or ultra-precise 32G sterile needles to limit injection trauma on dense scar tissue.
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Injection Depth: Must be placed strictly into the deep dermis. Placing the product too superficially can result in visible bumps that take longer to resolve, while subcutaneous deployment misses the scarred dermal layers completely.
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Treatment Regimen: A classic corrective protocol consists of 3 to 4 initial sessions, spaced precisely 4 weeks apart. For deep structural scars, combining this regimen with fractional CO2 laser or microneedling maximizes the regenerative outcome.
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Post-Treatment Guidelines: Localized swelling, minor redness, and transient micro-bumps at the injection points are standard physiological responses that fade naturally within 2 to 4 days. Patients must skip facial makeup for 24 hours and avoid saunas, swimming pools, and intense workouts for 3 to 5 days.
FAQ
Q: How does Rejuran S differ from Rejuran Healer and Rejuran I?
A: All three contain pure Polynucleotides (PN), but their viscosity is tailored for completely different structural needs. Rejuran I is the thinnest, lowest-viscosity gel, optimized for delicate skin around the eyes. Rejuran Healer is a medium-viscosity formula engineered for global face hydration and elasticity. Rejuran S is the thickest, highest-viscosity variant in the family, designed exclusively to stay localized beneath depressed scars and deep lines to provide powerful physical support and dense tissue remodeling.
Q: Is Rejuran S a temporary dermal filler?
A: No. While it provides an immediate mechanical lifting effect due to its high viscosity, Rejuran S is a regenerative bioremodeler, not a traditional HA filler. Its true objective is to heal the skin from within by replacing scarred, missing tissue with fresh, home-grown collagen. The long-term smoothing of the scar remains permanent even after the initial PN gel matrix has fully broken down.
Q: Can it be used on fresh, red acne scars?
A: Rejuran S is highly effective at modulating inflammation and speeding up tissue healing, making it beneficial for early-stage scars. However, it is most celebrated for correcting established, indented atrophic scars where a distinct loss of tissue volume has already occurred.
IMPORTANT NOTICE ON INTELLECTUAL PROPERTY
This store operates as an autonomous merchant of genuine medical aesthetic products. We maintain no formal affiliation, partnership, or authorized distribution agreement with PharmaResearch Product or the Rejuran brand family. All proprietary names, logos, and trademarks mentioned herein remain the exclusive intellectual property of their rightful owners. Their use on this site is strictly for the identification and description of the original goods we provide as an independent reseller.
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