Description
Rejuran S (the “S” standing for “Scar”) is a specialized, high-viscosity formulation from the South Korean Rejuran family, specifically engineered to treat depressed scars, acne scarring, and deep textural irregularities. Unlike traditional fillers that simply mask a scar by filling it with synthetic volume, Rejuran S acts as a biological scaffold. It utilizes the regenerative power of salmon-derived polynucleotides to stimulate the skin’s own healing mechanisms, effectively “lifting” the scar base by inducing the growth of healthy, new dermal tissue. This makes it a permanent structural improvement rather than a temporary aesthetic fix.
The Science of PN (Polynucleotide) for Tissue Repair
The efficacy of Rejuran S is derived from its concentrated PN (Polynucleotide) technology. While it shares the same salmon-DNA foundation as other Rejuran products, Rejuran S is uniquely characterized by its higher viscosity and gel-like consistency.
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Structural Scaffolding: Due to its thicker texture, Rejuran S provides an immediate, slight physical lift to depressed (atrophic) scars. This scaffold remains in place, providing a physical matrix that supports the migration and proliferation of fibroblasts.
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Intense Biostimulation: Polynucleotides are powerful DNA fragments that trigger the secretion of growth factors and the synthesis of new Type I and Type III collagen. This process gradually fills the “void” of a scar with the patient’s own natural tissue.
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Extracellular Matrix (ECM) Normalization: It helps to reorganize the chaotic collagen fibers often found in scarred tissue, promoting a smoother, more uniform skin texture that blends seamlessly with the surrounding healthy skin.
Clinical Indications and Scar Transformation
Rejuran S is the gold standard for patients seeking to improve the texture of their skin after trauma or inflammatory skin conditions. It is specifically indicated for:
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Acne Scarring: Highly effective for “boxcar” and “rolling” scars, where the skin needs both structural support and biological regeneration.
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Atrophic Scars: Treats depressed scars resulting from surgery, accidents, or chickenpox by stimulating tissue regrowth from the base of the lesion.
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Deep Wrinkles and Folds: Can be used on particularly deep, localized creases that require a more robust regenerative stimulus than standard skin boosters.
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Post-Laser Synergy: Often used in combination with fractional CO2 lasers or microneedling to maximize the remodeling phase and achieve superior skin smoothing.
Professional Protocol and Administration
As a potent regenerative treatment, Rejuran S must be administered exclusively by licensed medical professionals. The treatment focuses on the localized “subcision” and repair of scarred tissue.
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Injection Technique: The product is typically injected directly under the scar base using a fine needle. Many practitioners use a “subcision” technique, where the needle is used to break up the fibrous bands anchoring the scar before depositing the Rejuran S gel to prevent the scar from re-tethering.
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Recommended Protocol: For significant scar improvement, a series of 3 to 4 sessions is recommended, spaced 4 weeks apart. Because it relies on biological growth, the final results appear gradually as new collagen matures.
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Long-Term Results: Unlike hyaluronic acid fillers that dissolve over time, the tissue regenerated by Rejuran S is the patient’s own skin, leading to long-lasting structural improvements.
Safety and Authenticity
Rejuran S is a CE-certified medical device known for its excellent safety profile and high biocompatibility. Since salmon DNA is structurally similar to human DNA, the risk of allergic reactions is extremely low. To ensure maximum efficacy in scar remodeling, it is essential to source Rejuran S through authorized wholesale channels. This guarantees the integrity of the PN concentration and the sterility of the 1ml pre-filled syringe, ensuring the highest standards of patient care.
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