Description
Restylane Lyft with Lidocaine (formerly known as Perlane) is an elite, high-density, sterile injectable dermal filler engineered by Galderma for heavy-duty facial sculpting, deep structural volume restoration, and back-of-the-hand rejuvenation. Utilizing pioneering, proprietary NASHA™ Technology (Non-Animal Stabilized Hyaluronic Acid), Restylane Lyft features an exceptionally high G-prime (gel stiffness) and large particle size. This robust formulation delivers maximum lifting capacity and resistance to deformation, allowing practitioners to sculpt sharp cheekbone definitions, correct severe facial folds, and reverse significant age-related volume loss with ultimate predictability.
Main Benefits of Restylane Lyft
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Superior Structural Lifting: Engineered with a firm, high G-prime gel consistency that provides powerful projection and holds its shape exceptionally well under dense tissue pressure.
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Targeted Volume Restoration: Restores lost deep fat-pad volumes, lifting sagging midface structures and flattening deep anatomical folds.
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Proprietary NASHA™ Engineering: Composed of large, highly calibrated, minimally modified Hyaluronic Acid particles that resist chemical and mechanical flattening.
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Seamless Patient Comfort: Pre-infused with 0.3% Lidocaine Hydrochloride to instantly desensitize deep tissue layers and minimize discomfort during structural deployment.
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Clinically Proven Multi-Zone Versatility: The first dermal filler approved by the FDA for both deep midface augmentation and the correction of volume deficits on the back of the hands.
Indications
Restylane Lyft is indicated for deep dermal, subcutaneous, or supraperiosteal (on the bone) implementation to treat heavy tissue volume gaps:
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Cheek & Midface Augmentation: Rebuilding lost volume in the malar and sub-malar spaces while contouring a sharp zygomatic arch.
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Severe Nasolabial Folds: Lifting and smoothing deep, heavy creases running from the nose down to the oral commissures.
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Chin & Jawline Definition: Projecting weak chin profiles and creating sharp structural definitions along the mandibular border.
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Hand Biorejuvenation: Filling tissue hollows on the dorsum (back) of the hands to obscure prominent tendons, veins, and bony structures.
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Deep Temples: Correcting advanced temporal hollowing to restore smooth, youthful upper-facial lines.
Technical Specifications
| Feature | Specification |
| Product Name | Restylane Lyft with Lidocaine |
| Manufacturer | Galderma |
| Active Ingredient | Stabilized Hyaluronic Acid (NASHA™ – Large Particles) |
| HA Concentration | 20 mg/mL |
| Anesthetic Integration | 0.3% Lidocaine Hydrochloride |
| Packaging | 1 x 1ml Pre-filled syringe per box |
| Needles Included | 2 x 29G 1/2″ sterile single-use needles |
| Application Layer | Deep dermis / Subcutaneous / Supraperiosteal |
| Duration of Effect | 10 to 12 months (up to 6 months in hands) |
| Storage | Store between 2°C to 25°C; protect from freezing and direct sunlight |
Mechanism of Action
The filler operates via Large-Particle Mechanical Suspension:
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Deep Structural Elevation: When placed deep on the bone (supraperiosteal) or within the deep fat pads, the rigid NASHA particles act as dense microscopic pillars, projecting the overlying tissue upward.
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Tissue Anchor Integrity: The high cohesiveness of the gel blocks product migration, ensuring that the volume remains exactly where it was positioned by the injector.
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Hydrophilic Framework Retention: The pure HA structure binds water molecules tightly inside the deep dermal spaces, maintaining local thickness and skin hydration levels.
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Enzymatic Shielding: Because the large gel particles are heavily clustered and cross-linked, natural hyaluronidase enzymes require 10 to 12 months to fully clear the core matrix.
Administration Protocol
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Technique: Administered using a precise deep bolus injection (when anchoring on bone), retrograde fanning, or linear threading patterns.
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Injection Tool: Can be delivered using the provided 29G needles or an advanced 22G to 25G blunt-tipped cannula to safely cross dense fat networks and minimize vascular compromises.
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Injection Depth: Must be placed strictly into the deep dermis, deep subcutaneous layers, or supraperiosteal space. Overly superficial injection will lead to visible structural bumps, discoloration (Tyndall effect), or vascular complications.
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Post-Treatment Care: Firm manual molding must be applied immediately post-injection to form an absolute, smooth contour. Patients should avoid pushing hard on the treated zones, skip intense exercise, and avoid hot saunas for 48 hours.
FAQ
Q: How does Restylane Lyft differ from classic Restylane?
A: While both are formulated with 20mg/mL HA via NASHA technology, Restylane Lyft uses significantly larger gel particles. This makes Lyft a much firmer, highly viscous gel engineered exclusively for deep tissue lifting, cheekbones, and volume restoration. Classic Restylane is softer and optimized for medium wrinkles, tear troughs, and lip lines.
Q: Is there downtime after getting Restylane Lyft?
A: Downtime is low. Because it is deployed in deeper facial layers, surface tissue trauma is limited. However, some deep tenderness, minor localized swelling, and pinpoint bruising can occur at the entry sites, normally resolving within 3 to 7 days.
Q: Can Restylane Lyft be dissolved if overcorrected?
A: Yes, absolutely. Despite its heavy structural lifting capabilities and high density, Restylane Lyft is made from pure, non-animal Hyaluronic Acid. The entire matrix can be completely and rapidly dissolved within hours using standard professional hyaluronidase solutions (such as Liporase).
IMPORTANT NOTICE ON INTELLECTUAL PROPERTY
This store operates as an autonomous merchant of genuine medical aesthetic products. We maintain no formal affiliation, partnership, or authorized distribution agreement with Galderma, its global subsidiaries, or the Restylane brand family. All proprietary names, logos, and trademarks mentioned herein remain the exclusive intellectual property of their rightful owners. Their use on this site is strictly for the identification and description of the original goods we provide as an independent reseller.






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