Rejeunesse Deep Lidocaine Volumization Filler

Description

Rejeunesse Deep with Lidocaine is a highly versatile, medium-density injectable dermal filler developed by Newmedic Co., Ltd. (South Korea). Formulated as a highly pure, monophasic cross-linked Hyaluronic Acid (HA) gel, this product is specifically engineered to treat moderate-to-deep facial wrinkles, nasal folds, and structural contour depressions. Utilizing proprietary UPHEC Technology (Unique Purification High-Concentration Essential Cross-linking), the gel undergoes a rigorous triple-purification process that thoroughly structures the HA matrix while removing residual chemical cross-linkers and endotoxins. Rejeunesse Deep features an optimal elastic modulus (G-Prime) that balances strong mechanical lifting power with smooth, flexible tissue integration. Infused with 0.3% Lidocaine Hydrochloride to maximize patient comfort during the procedure, it provides an immediate plumpness, uniform volume distribution, and highly reliable shape retention.

Main Benefits of Rejeunesse Deep with Lidocaine

• Superior Lip Sculpting & Volumization: Offers excellent cohesion and plastic elasticity, making it a favorite for creating defined lip borders (Cupid’s bow) and plump, natural-looking lip body volume.

• UPHEC Triple-Purification Safety: Advanced manufacturing minimizes unlinked BDDE residues, resulting in an exceptionally pure gel that drastically reduces post-procedure swelling, edema, and allergic reactions.

• Smooth, Post-Injection Symmetry: The uniform monophasic gel flows with a constant, predictable extrusion force, allowing injectors to achieve highly precise, symmetrical facial sculpting without surface lumps.

• Integrated Local Anesthetic: Packed with 0.3% Lidocaine Hydrochloride to effectively numb the local tissue, ensuring a comfortable, pain-free injection experience across highly sensitive zones.

• Extended Viscoelastic Longevity: The highly cross-linked HA matrix resists natural enzymatic breakdown, providing stable structural volume that remains beautifully intact for 12 to 18 months.

Indications

Rejeunesse Deep is specifically indicated for mid-to-deep dermal or subcutaneous injections to fill moderate creases, augment soft tissues, and refine regional profiles:

• Lip Augmentation & Border Definition: Adding balanced volume, restoring symmetry, and sharpening the perioral borders of the lips.

• Moderate-to-Deep Nasolabial Folds: Plumping the dynamic deep expression lines that run from the wings of the nose down to the corners of the mouth.

• Marionette Lines & Oral Commissures: Lifting drooping corners of the mouth and smoothing out creases extending toward the jawline.

• Glabellar Frown Lines & Deep Forehead Furrows: Filling deeply set structural lines across the brow area that require a firmer gel matrix.

• Mild Facial Contouring: Restoring soft, natural volume to depleted cheeks, the chin apex, or the submalar hollows.

Technical Specifications

Feature	Specification
Product Name	Rejeunesse Deep with Lidocaine
Manufacturer	Newmedic Co., Ltd. / MediPharma Research (South Korea)
Active Substrate	Monophasic Cross-Linked Hyaluronic Acid (HA)
HA Concentration	24 mg/mL
Local Anesthetic	Lidocaine Hydrochloride (0.3% w/v)
Crosslinking Tech	BDDE cross-linked via UPHEC Technology
Packaging Layout	1 x 1.1ml Pre-filled sterile single-use glass syringe per box
Total Fluid Yield	1.1ml total treatment volume per retail box
Included Needles	1 x 27G sterile single-use needle
Injection Layer	Mid-to-deep dermis or subcutaneous tissue layer
Duration of Results	12 to 18 months (depending on individual metabolism and movement)
Storage Parameters	Store between 2°C to 25°C; protect from extreme heat, direct sunlight, and freezing

Mechanism of Action

Rejeunesse Deep achieves medium structural correction through a balanced Cohesive Dermal Integration pathway:

1. Immediate Mechanical Correction: Once deposited into the mid-to-deep dermis, the uniform monophasic gel works instantly as a structural cushion, filling deep tissue deficits and smoothing moderate folds immediately.

2. Hydrophilic Volume Expansion: The non-animal HA molecules absorb surrounding water molecules up to 1,000 times their own dry weight, providing localized structural fullness and maintaining deep tissue hydration.

3. High-Resistance Cross-Linked Network: Thanks to UPHEC processing, the tightly woven HA chains are resistant to rapid breakdown by endogenous hyaluronidase enzymes. The gel degrades evenly over months, retaining a stable, uniform lifting effect throughout its lifecycle.

Administration Protocol

• Delivery Formats: Administered solely by licensed medical professionals using tailored injection techniques. Typical approaches include linear retrograde threading, bolus deposition (for chin/cheek touch-ups), and micro-droplet or fanning patterns using a 27G needle or a 25G / 27G blunt micro-cannula to shape lips and folds safely.

• Optimal Placement Depth: Must be placed cleanly within the mid-to-deep dermis or the superficial subcutaneous fat layer. Shallow delivery in the upper dermis must be avoided to prevent visible lumps or a bluish tint under the skin surface (Tyndall effect).

• Post-Injection Management: The injector should firmly mold the treated areas immediately following delivery to blend the gel smoothly into the surrounding facial contours. Patients may experience mild, temporary swelling, pinpoint redness, or bruising. Advise them to avoid intense physical exercise, alcohol, saunas, and hot environments for 24 to 48 hours.

FAQ

Q: Can Rejeunesse Deep be dissolved if a patient desires a correction?

A: Yes. Because Rejeunesse Deep is composed entirely of cross-linked hyaluronic acid, it can be quickly and completely dissolved using standard prescription hyaluronidase enzymes if an adverse event occurs or if a complete reversal is requested.

Q: What makes Rejeunesse Deep different from Rejeunesse Fine and Rejeunesse Shape?

A: The difference lies within the gel’s particle thickness and structural density. Rejeunesse Fine is soft and thin, designed for superficial lines and tear troughs. Rejeunesse Deep features medium-density particles tailored for lips and moderate folds in the mid-to-deep dermis. Rejeunesse Shape is the thickest gel in the range, formulated strictly for deep subcutaneous or bone-level placement to provide heavy structural augmentation (chin, cheeks, nose).

Q: Is this product suitable for treating tear troughs or under-eye hollows?

A: No. Rejeunesse Deep is too dense for the delicate, paper-thin periorbital zone. Injecting it under the eyes carries a high risk of creating visible lumps, over-correction, and chronic fluid retention. For under-eye hollows, a lighter formulation like Rejeunesse Fine is much more appropriate.

IMPORTANT NOTICE ON INTELLECTUAL PROPERTY

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