Dermaheal HSR – Hyaluronic Acid & Peptide

Description

Dermaheal HSR (Hyaluronic Skin Rejuvenating Solution) is a powerful, dual-action mesotherapy formulation engineered by Caregen (South Korea) to treat mature, chronically dry, or sun-damaged skin. Elevating the standard rejuvenating complex, this intensive solution combines 1% (10 mg/mL) high-purity, uncrosslinked Hyaluronic Acid with an ultra-concentrated matrix of 57 active ingredients, including 5 specific biomimetic peptides, 13 vitamins, 24 amino acids, 5 minerals, 4 coenzymes, and 4 nucleic acids. Dermaheal HSR rehydrates the tissue matrix immediately while sending deep biological commands to stimulate aging fibroblasts. By rebuilding the extracellular matrix and boosting structural cell growth, it reduces the depth of wrinkles, tightens loose skin textures, and restores a plump, radiant, and deeply hydrated complexion.

Main Benefits of Dermaheal HSR

• Dual-Action Hydro-Firming: Infuses a 1% concentration of pure hyaluronic acid to instantly smooth surface dryness while biomimetic peptides work beneath to restore structural thickness.

• Targeted Fine Line & Wrinkle Erasure: Visibly smooths superficial creases, fine forehead lines, crow’s feet, and early perioral folds by stimulating fresh collagen synthesis.

• Fibroblast & Collagen Rebuilding: Uses advanced cell messengers to wake up slow dermal fibroblasts, stepping up the natural production of Type I collagen and elastin fibers.

• Intense Cellular Hydration: Locks major moisture directly into thinned, tired, or parched skin layers, bringing back a bouncy, youthful suppleness.

• Complete Dermal Nourishment: Floods depleted skin with 24 foundational amino acids and 13 essential vitamins to smooth rough patches, clear skin fatigue, and maximize cell repair.

Indications

Dermaheal HSR is engineered for broad mesotherapy injection sequences, targeted micro-needling, or professional device-assisted delivery across aged, dry, or damaged skin profiles:

• Mature Skin & Chronological Aging: Treating fine wrinkles, noticeable loss of elasticity, and structural thinning (typically ages 30 and up).

• Severe Hydro-Dermal Depletion: Rehydrating complexions showing chronic flakiness, deep dullness, or weather-worn surfaces.

• Loss of Architectural Elasticity: Firming loose or saggy areas along the jawline, lower cheeks, neck, and upper chest.

• Stretch Marks & Atrophic Irregularities: Boosting skin repair to soften the texture and depth of old stretch marks or shallow post-breakout scars.

Technical Specifications

Feature	Specification
Product Name	Dermaheal HSR (Hyaluronic Skin Rejuvenating Solution)
Manufacturer	Caregen Co., Ltd. (South Korea)
Active Hyaluronic Acid	1% (10 mg/mL) non-crosslinked, bio-fermented Sodium Hyaluronate
5-Biomimetic Peptide Blend	Oligopeptide-24 (CG-EDP3), Decapeptide-4 (CG-IDP2), Acetyl Decapeptide-3 (Rejuline), Tripeptide-6 (CG-CTP), Copper Tripeptide-1
Complete Nutrient Array	13 Vitamins, 24 Amino Acids, 5 Minerals, 4 Coenzymes, 4 Nucleic Acids, 2 Reducing Agents
Packaging Layout	10 x 5ml Sterile glass vials per retail box
Total Liquid Volume	50ml total yield per single package
Injection Layer	Superficial to mid-dermis (Epidermal-dermal junction)
Delivery Methods	Micro-papule mesotherapy, Microneedling (Dermapen/Dermaroller), or Post-Treatment Topical Coating
Standard Session Protocol	1 intensive phase of 4 to 8 weekly treatments, followed by monthly maintenance
Storage Parameters	Store between 2°C to 25°C; avoid freezing; use open vials within 5 days under refrigeration

Mechanism of Action

Dermaheal HSR targets advanced dermal structural breakdown through a synchronized Tri-Phase Matrix Optimization model:

1. Immediate Micro-Plumping Hydro-Grid: The uncrosslinked hyaluronic acid immediately spreads out into the spaces between dermal cells. It holds hundreds of times its weight in water, smoothing dry creases and lifting up sunken superficial profiles.

2. Peptide-Driven Neo-Collagenesis: Oligopeptide-24 and Decapeptide-4 match up with fibroblast surface receptors, signaling the cells to speed up division. At the same time, Acetyl Decapeptide-3 and Tripeptide-6 switch on the production of dense collagen and elastin networks to tighten loose skin.

3. Vascular Support & Tissue Re-Texturing: Copper Tripeptide-1 improves blood microcirculation, ensuring proper oxygen delivery to newly active cells while clearing out old, damaged matrix proteins to smooth out rough textures.

Administration Protocol

• Delivery Formats: Administered by licensed aesthetic professionals via manual micro-papule arrays, advanced multi-needle mesotherapy injectors, or medical-grade microneedling (dermapen/dermaroller) systems.

• Optimal Placement Depth: Must be placed cleanly into the superficial or mid-dermis, target depths ranging from 1.0mm to 1.5mm. Punctures are distributed in a tight grid format across the face and neck, with injection points spaced approximately 0.5cm to 1cm apart.

• The Recommended Session Cycle:

  • Phase 1 (Intensive Loading): 1 treatment session every week for the first 4 to 8 weeks.

  • Phase 2 (Stabilization): 1 treatment every 2 weeks for an additional month.

  • Phase 3 (Maintenance): 1 booster session every 4 to 6 weeks to sustain tissue hydration, plumpness, and wrinkle defense.

• Post-Treatment Guidelines: Small, temporary papules, mild redness, or slight swelling can appear at the entry points, clearing up within 12 to 24 hours. Patients must keep the skin bare and avoid washing for 24 hours. High-intensity workouts, steam baths, saunas, and direct sun exposure should be avoided for 48 hours.

FAQ

Q: What is the main difference between Dermaheal HSR and Dermaheal SR?

A: Both serums share an identical nourishing foundation of 56 ingredients and 5 biomimetic peptides. However, Dermaheal HSR includes an added 1% (10 mg/mL) concentration of high-purity Hyaluronic Acid. This makes HSR ideal for mature, dry skin profiles requiring immediate deep hydration and wrinkle plumping. Dermaheal SR is free of this added hyaluronic acid, making it better suited for oily, combination, or younger skin types focused purely on shrinking pores and smoothing out early texturing.

Q: Can Dermaheal HSR be used alongside crosslinked dermal fillers?

A: Yes. Dermaheal HSR treats the entire skin layer to improve general hydration, thickness, and elasticity, whereas traditional crosslinked dermal fillers are placed deep in localized zones to replace lost fat or bone volume (like cheeks or lips). Combining both treatments provides a more complete, natural-looking facial rejuvenation.

Q: How soon will my patients notice a difference?

A: Surface hydration improves almost instantly, giving the skin a fresh, soft feel a day or two after the first treatment. Structural transformations—such as less noticeable fine lines, a firmer jawline, and balanced skin elasticity—develop over the course of the loading protocol, peaking between weeks 4 and 6.

IMPORTANT NOTICE ON INTELLECTUAL PROPERTY

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