Liporase Hyaluronidase 10 Vials – Filler Dissolving

Description

Liporase is a highly purified, professional-grade freeze-dried hyaluronidase enzyme designed to break down and dissolve hyaluronic acid (HA) fillers quickly and effectively. With a potent concentration of 1500 International Units (IU) per vial, Liporase acts as an essential rescue and correction tool in aesthetic medicine. It is widely used by practitioners to reverse unwanted filler results, treat overfilled areas, correct asymmetry, or manage emergency complications such as accidental vascular occlusions.

Main Benefits of Liporase

• Rapid Filler Reversal: Dissolves cross-linked hyaluronic acid fillers within minutes, offering an immediate solution to aesthetic complications or patient dissatisfaction.

• Precision Correction: Allows practitioners to selectively remove misplaced or migrated filler, smooth out stubborn lumps, and eliminate the “Tyndall effect” (bluish skin discoloration).

• Emergency Complication Management: Serves as the primary emergency agent to clear blocked blood vessels caused by accidental intravascular filler injection, preventing tissue necrosis.

• Enhanced Tissue Permeability: Functions as a powerful spreading agent, temporarily reducing tissue viscosity to improve the absorption and dispersion of other injected solutions, such as local anesthetics or lipolytic cocktails.

• High Potency & Stability: The freeze-dried powder formulation ensures excellent stability and a long shelf life when stored correctly before reconstitution.

Indications

Liporase 1500 IU is an indispensable asset for advanced aesthetic clinics, indicated for:

• Hyaluronic Acid Dissolution: Removing or reshaping unwanted dermal fillers.

• Vascular Occlusion Interventions: Restoring immediate blood flow during ischemic events.

• Filler Migration: Correcting filler that has drifted away from the original injection site (e.g., lip filler migration).

• Enhancing Local Anesthesia: Speeding up the onset and spread of anesthetics during surgical or dental procedures.

• Lipolysis Optimization: Combining with fat-dissolving treatments to maximize the distribution and effectiveness of the active ingredients.

Technical Specifications

Feature	Specification
Product Name	Liporase
Active Ingredient	Hyaluronidase (highly purified)
Potency	1500 IU (International Units) per vial
Packaging	10 Vials of lyophilized (freeze-dried) powder
Form	White or yellowish-white vacuum-dried cake/powder
Storage	Store in a refrigerator (2°C to 8°C) or cool place; do not freeze
Application Depth	Subcutaneous or intradermal (directly into the filler deposit)

Mechanism of Action

Liporase operates through Enzymatic Depolymerization:

1. Bond Cleavage: Upon injection, the hyaluronidase enzyme immediately begins hydrolyzing the glucosaminidic bonds of both natural and cross-linked hyaluronic acid.

2. Liquefaction: This chemical breakdown transitions the dense, cohesive filler gel into a fluid state, drastically lowering its local viscosity.

3. Lymphatic Clearance: The fragmented HA molecules are rapidly recognized by the body’s natural defense systems and are absorbed and cleared via the lymphatic system.

4. Temporary Tissue Modification: The increased permeability of the intercellular matrix lasts for approximately 24 to 48 hours, after which the skin naturally replenishes its own native hyaluronic acid levels.

Administration Protocol

• Reconstitution: Mix one vial of Liporase (1500 IU) with sterile 0.9% Sodium Chloride (Saline). The amount of saline added depends on the desired clinical concentration. A common protocol involves adding 3mL to 5mL of saline to achieve a workable concentration per 0.1mL.

• Skin Patch Test: Because hyaluronidase is a foreign protein, it is highly recommended to perform a subcutaneous patch test on the patient’s forearm prior to a full treatment to rule out hypersensitivity or allergic reactions.

• Injection Technique: Using an ultra-fine needle (30G or 32G), inject the reconstituted solution directly into the specific pocket or nodule of the misplaced HA filler.

• Immediate Timeline: The enzymatic action begins on contact. While initial softening happens within minutes, the final aesthetic outcome should be evaluated after 48 to 72 hours once temporary swelling subsides.

• Professional Note: Liporase is exclusively effective against Hyaluronic Acid. It will not alter or dissolve non-HA materials such as Calcium Hydroxylapatite (Radiesse), PLLA (Sculptra), or permanent silicone.

FAQ

Q: How many vials of Liporase come in a box?

A: Each box contains a complete set of 10 single-use vials of lyophilized powder, making it highly economical for clinics managing high volumes of corrective procedures.

Q: How long must a patient wait before getting filler re-injected?

A: It is critical to wait at least 10 to 14 days after using Liporase before re-introducing new HA fillers. This ensures that the injected enzyme is completely inactive and will not instantly dissolve the newly placed filler.

Q: Will Liporase dissolve the patient’s natural skin structure?

A: While Liporase may temporarily break down some of the skin’s native hyaluronic acid along with the filler, the effect is entirely transient. The skin’s natural metabolic processes regenerate native HA within 24 to 48 hours, leaving no permanent structural defects.

IMPORTANT NOTICE ON INTELLECTUAL PROPERTY

This store operates as an autonomous merchant of genuine medical aesthetic products. We maintain no formal affiliation, partnership, or authorized distribution agreement with the manufacturers of Liporase or their global subsidiaries. All proprietary names, logos, and trademarks mentioned herein remain the exclusive intellectual property of their rightful owners. Their use on this site is strictly for the identification and description of the original goods we provide as an independent reseller.