Radiesse Lidocaine (1.5ml) – Calcium Hydroxylapatite

Description

Radiesse Lidocaine is an advanced, dual-action injectable dermal filler and biostimulator engineered by Merz Aesthetics (Germany) to correct moderate-to-severe facial wrinkles, restore deep tissue volume, and define sharp structural contours. Composed of high-purity Calcium Hydroxylapatite (CaHA) microspheres (30%) suspended in a cohesive, water-based Sodium Carboxymethylcellulose (CMC) gel carrier (70%), this unique formulation provides immediate structural lifting alongside long-term tissue remodeling. The solution is enhanced with 0.3% Lidocaine Hydrochloride to minimize patient discomfort during deep placement. Radiesse Lidocaine does not merely fill wrinkles; it serves as a biological scaffold that triggers neocollagenesis (the synthesis of new collagen) and elastin production, restoring the skin’s natural architectural thickness and elasticity.

Main Benefits of Radiesse Lidocaine

• Immediate Mechanical Lifting: The high-viscosity CMC gel carrier provides instant projection and volume correction to fill deep folds and smooth structural hollows upon injection.

• Long-Term Biostimulation: The CaHA microspheres act as a framework that activates fibroblasts, driving the production of fresh Type I and Type III collagen and elastin fibers.

• Integrated Patient Comfort: Formulated with 0.3% Lidocaine to numb the local tissue, ensuring a smooth and comfortable experience during deep injection.

• High Structural Elasticity: Boasts an exceptional G-Prime (elastic modulus), providing precise projection that holds its shape under heavy facial movement without spreading or flattening.

• Extended Durability: Delivers aesthetic corrections that last significantly longer than standard non-crosslinked and many crosslinked hyaluronic acid fillers, remaining effective for 12 to 18+ months.

Indications

Radiesse Lidocaine is specifically engineered for deep subdermal, deep dermal, or pre-periosteal injections to treat volume loss, structural contours, and deep facial folds:

• Severe Nasolabial Folds & Marionette Lines: Filling deep expression lines that frame the mouth and nose.

• Cheek, Malar, and Submalar Augmentation: Rebuilding lost fat pads and projecting flat cheekbones.

• Jawline Contouring & Pre-Jowl Sulcus: Sharpening loose or saggy jawline perimeters and filling jaw notches.

• Chin Augmentation: Projecting and contouring weak or recessed chins to achieve profile balance.

• Dorsal Hand Rejuvenation: Filling sunken spaces between tendons and veins on the backs of the hands to restore a smooth appearance.

Technical Specifications

Feature	Specification
Product Name	Radiesse Lidocaine
Manufacturer	Merz Aesthetics (Germany)
Active Composition	30% Calcium Hydroxylapatite (CaHA) Microspheres (25-45 microns)
Carrier Component	70% Sodium Carboxymethylcellulose (CMC) Gel Matrix
Local Anesthetic	Lidocaine Hydrochloride (0.3% w/w)
Packaging Layout	1 x 1.5ml Pre-filled sterile single-use glass syringe
Total Liquid Volume	1.5ml total yield per retail box
Injection Layer	Deep subdermal, deep dermal, or pre-periosteal (on top of bone)
Common Needle/Cannula	27G / 28G needle or 22G / 25G blunt micro-cannula
Duration of Results	12 to 18+ months (depending on patient metabolism and depth)
Storage Parameters	Store between 15°C to 25°C; protect from extreme heat, light, and freezing

Mechanism of Action

Radiesse Lidocaine remodels facial architecture through a precise Dual-Phase Tissue Regeneration pathway:

1. Immediate Volumizing Phase: Upon injection, the cohesive carboxymethylcellulose (CMC) gel matrix acts as an instant mechanical cushion, pushing up sunken dermal layers to smooth away lines and provide immediate projection.

2. Fibroblastic Scaffold Activation: Over the next 2 to 3 months, local enzymes naturally break down the CMC gel, leaving behind the neat grid of CaHA microspheres. These spheres stimulate surrounding fibroblasts to wrap around them, spinning a thick, fresh network of Type I collagen and structural elastin fibers.

3. Natural Tissue Integration: As the CaHA microspheres slowly break down into calcium and phosphate ions over 12 to 18 months, they leave behind a strong, self-supporting scaffold of the patient’s own natural collagen fibers.

Administration Protocol

• Delivery Formats: Administered exclusively by licensed medical professionals using advanced injection strategies. These include linear retrograde threading for deep lines, bolus placement directly onto the bone for chin/malar projection, or fanning vectors with a blunt micro-cannula for the jawline and hands.

• Optimal Placement Depth: Must be placed cleanly into the deep subdermal plane or pre-periosteally. Shallow placement in the superficial dermis must be strictly avoided to prevent visible nodules, skin blanching, or surface irregularities.

• Hyper-Dilution Technique (Optional): For wide-area skin tightening on the neck, chest, or arms, Radiesse can be hyper-diluted with sterile saline or lidocaine. This method removes its immediate volumizing effect, focusing purely on spreading long-term biostimulatory collagen production across a broad area.

• Post-Procedure Care: Firm massage should be performed immediately after injection to ensure the product blends smoothly with the surrounding tissue contours. Patients may experience mild swelling, tenderness, or bruising. They should avoid intense facial pressure, heavy exercise, saunas, and sun exposure for 24 to 48 hours.

FAQ

Q: Can Radiesse Lidocaine be dissolved if a mistake is made?

A: No. Unlike hyaluronic acid fillers, which can be dissolved quickly with hyaluronidase enzymes, Calcium Hydroxylapatite (CaHA) cannot be dissolved. Therefore, precise placement by an experienced medical professional who understands facial anatomy and deep-layer injection techniques is essential.

Q: Can Radiesse Lidocaine be injected into the lips or under the eyes?

A: No. Radiesse Lidocaine is strictly contraindicated for use in the lips (vermilion border/body) and the tear troughs (under-eye area). Injecting into these highly mobile, thin-skinned zones carries a high risk of developing visible white nodules and lumps.

Q: When do the long-term biostimulatory effects become visible?

A: While the mechanical lifting effect is immediate thanks to the CMC gel, the long-term firming and restructuring benefits develop gradually. This structural shift peaks around month 3 as the fibroblasts build fresh networks of collagen and elastin fibers, sustaining the look for 12 to 18 months.

IMPORTANT NOTICE ON INTELLECTUAL PROPERTY

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